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Dental Local Anesthesia Drugs Paracetamol 103-90-2 Pain Reliever Drug

Categories Pharmaceutical Raw Materials
Brand Name: HKYC
Model Number: HKYC
Certification: ISO 9000, SGS
Place of Origin: HUBEI,CHINA
MOQ: 10grams
Price: negotiable(best offer will be provided)
Payment Terms: MoneyGram, Western Union, T/T, Bitcoin
Supply Ability: 1000Kg per Month
Delivery Time: within 24hours after payment confirm
Packaging Details: designed disguised packing ways, 100% pass custom guarantee)
CAS: 103-90-2
Appearance: White Powder
Molecular Formula: C8H9NO2
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Dental Local Anesthesia Drugs Paracetamol 103-90-2 Pain Reliever Drug

Dental Local Anesthesia Drugs Paracetamol 103-90-2 Pain Reliever Drug
roduct Name:Paracetamol

Alias: 4-Acetamidophenol;4'-HYDROXYACETANILIDE;4-HYDROXYACETANILIDE;ACETYL-P-AMINOPHENOL
CAS: 103-90-2
EINECS: 203-157-5
M.F.: C8H9NO2
M.W.: 151.16
Product Category: Pharmaceutical raw materials and intermediates
Product content: 98.0% -102.0%
Quality Standard: cp2000/bp98/usp23
Packing Specification: 25KG / plastic woven bag or 25KG / fiber drum
Appearance: white crystal or crystalline powder
Usage: Antipyretic analgesic bulk drugs
Paracetamol Descriptions

This product is acetanilide antipyretic analgesics. By inhibiting ring oxidase and selectivity in the hypothalamus of the temperature regulating center, the synthesis of prostaglandins in peripheral vascular expansion, sweating and antipyretic effect, strength of its antipyretic effect similar to aspirin.

Paracetamol Function

Antipyretic analgesic:
This product is acetanilide antipyretic analgesics. By inhibiting ring oxidase and selectivity in the hypothalamus of the temperature regulating center, the synthesis of prostaglandins in peripheral vascular expansion, sweating and antipyretic effect, strength of its antipyretic effect similar to aspirin
Pharmacodynamics
Acetaminophen (USAN) or Paracetamol (INN) is a widely used analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. It is a major ingredient in numerous cold and flu medications and many prescription analgesics. It is extremely safe in standard doses, but because of its wide availability, deliberate or accidental overdoses are not uncommon. Acetaminophen, unlike other common analgesics such as aspirin and ibuprofen, has no anti-inflammatory properties or effects on platelet function, and it is not a member of the class of drugs known as non-steroidal anti-inflammatory drugs or NSAIDs. At therapeutic doses acetaminophen does not irritate the lining of the stomach nor affect blood coagulation, kidney function, or the fetal ductus arteriosus (as NSAIDs can). Like NSAIDs and unlike opioid analgesics, acetaminophen does not cause euphoria or alter mood in any way. Acetaminophen and NSAIDs have the benefit of being completely free of problems with addiction, dependence, tolerance and withdrawal. Acetaminophen is used on its own or in combination with pseudoephedrine, dextromethorphan, chlorpheniramine, diphenhydramine, doxylamine, codeine, hydrocodone, or oxycodone.

Mechanism of action
Acetaminophen is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Unlike NSAIDs, acetaminophen does not inhibit cyclooxygenase in peripheral tissues and, thus, has no peripheral anti-inflammatory affects. While aspirin acts as an irreversible inhibitor of COX and directly blocks the enzyme's active site, studies have found that acetaminophen indirectly blocks COX, and that this blockade is ineffective in the presence of peroxides. This might explain why acetaminophen is effective in the central nervous system and in endothelial cells but not in platelets and immune cells which have high levels of peroxides. Studies also report data suggesting that acetaminophen selectively blocks a variant of the COX enzyme that is different from the known variants COX-1 and COX-2. This enzyme is now referred to as COX-3. Its exact mechanism of action is still poorly understood, but future research may provide further insight into how it works. The antipyretic properties of acetaminophen are likely due to direct effects on the heat-regulating centres of the hypothalamus resulting in peripheral vasodilation, sweating and hence heat dissipation.


competitive Advantage:

1. Our company is a professional production leading factory in China in pharmaceutical area of many years. Delivery areas of our products:US, UK, Canada, Australia, Brazil, Russia, Portugal, Latvia, Switzerland, Iceland, Ukraine, Germany, France, Netherlands, Belgium, Peru, Sweden, New Zealand, the Czech Republic, Lithuania, Ireland, Tunisia, Mexico, Greece, Puerto Rico, Thailand, Israel and so on.

Payment method: T/T, Western union, Moneygram
2. Discreet package .The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also take into consideration .
3. Top quality. High quality guaranteed, once any problem is found, the package would be reshipped for you .
4. Security Shipping:Shipping by express (FedEx,UPS,DHL,EMS), by air.The most professional forwarder would be recommanded for you.
5. We have stock, so we can delivery quickly at the very day when receive the payment.
6. Warm after-sale service for you 24/7. Any of your question would be solved for the first as soon as possible.
7. A discount would be given when you make a large order.



Supply Ability: Mass Stock

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Cheap Dental Local Anesthesia Drugs Paracetamol 103-90-2 Pain Reliever Drug for sale
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